Can i take doxylamine succinate while nursing

Learn how we develop our content. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. Updated visitor guidelines. You are here Home » doxylamine. Top of the page. Pronunciation: dox IL a meen Brand: Unisom. What is the most important information I should know about doxylamine? What is doxylamine? Doxylamine is also used as a short-term treatment for sleep problems insomnia. Doxylamine may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before taking doxylamine? You should not use doxylamine if you are allergic to it. How should I take doxylamine? Take this medicine with food or milk if it upsets your stomach. What happens if I miss a dose? What happens if I overdose? Seek emergency medical attention or call the Poison Help line at What should I avoid while taking doxylamine? Drinking alcohol can increase certain side effects of doxylamine.

What are the possible side effects of doxylamine? What other drugs will affect doxylamine? Doxylamine Unsafe.

Promethazine Low Risk. Droperidol Low Risk. Prochlorperazine Unsafe. Metoclopramide Safe. Trimethobenzamide Unsafe. Cyclizine Low Risk. Epinastine Low Risk. Triprolidine Safe. Dexchlorpheniramine Low Risk. Levocetirizine Low Risk. Pyrilamine Low Risk. Desloratadine Safe. Clemastine Low Risk. Ketotifen Low Risk. Chlorpheniramine Low Risk. Loratadine Safe. Cetirizine Safe. Carbinoxamine Low Risk. Hydroxyzine Safe. Brompheniramine Low Risk.

Fexofenadine Safe. Azelastine Low Risk. Diphenhydramine Low Risk. Acrivastine Low Risk. Octreotide Safe. Bismuth Subsalicylate. PMID: 2. Histamine H1 receptor participation in the control of prolactin secretion in postpartum. J Endocrinol Invest. PMID: 3. The effect of histamine and H1 and H2 receptors on prolactin and luteinizing hormone release in humans: sex differences and the role of stress.

J Clin Endocrinol Metab. A first generation ethanolamine with antiinflammatory, sedative and antihistamine properties. Doxylamine competitively inhibits the histamine 1 H1 receptor, thereby preventing the action of endogenous histamine as well as the subsequent release of pro-inflammatory mediators from basophils and mast cells.

This agent acts as an inverse agonist that combines with, and stabilizes the inactive form of the H1-receptor, shifting the H1 receptor equilibrium toward the inactive state. This results in downregulation of nuclear factor-kappaB NF-kappaB and NF-kappaB dependent antigen presentation, chemotaxis, as well as expression of cell-adhesion molecules and pro-inflammatory cytokines.

Small occasional doses of doxylamine would not be expected to cause any adverse effects in breastfed infants.