How does acanthosis nigricans occur

Treating the underlying cause of acanthosis nigricans can make the dark patches of skin fade or even disappear. Losing weight will help acanthosis nigricans fade. Doctors may prescribe creams or lotions that can help lighten the skin. Scrubbing the skin does not help and can irritate it. Eating a healthy diet and getting regular physical activity can help lower insulin levels and improve skin appearance. It can help to:. Reviewed by: Mary L. Gavin, MD. Larger text size Large text size Regular text size.

What Is Acanthosis Nigricans? What Causes Acanthosis Nigricans? Acanthosis nigricans Acanthosis nigricans. It is very important to differentiate acanthosis nigricans related to malignancy from that related to benign conditions. Tumours in malignant acanthosis nigricans are usually very aggressive and spread quickly. Death often occurs soon after. If malignant acanthosis nigricans is suspected in a patient without known cancer, it is extremely important to perform a thorough workup for underlying malignancy and identify a hidden tumour.

If the tumour can be successfully treated, the condition may resolve. Other causes of acanthosis nigricans may be identified by screening for insulin resistance and diabetes mellitus. The primary aim of treatment is to correct the underlying disease process. Often correcting the underlying cause results in resolution of the lesions. There is no specific treatment for acanthosis nigricans.

Treatments considered are used primarily to improve cosmetic appearance and include topical retinoids , dermabrasion and laser therapy. Final outcome of acanthosis nigricans varies depending on the cause of acanthosis nigricans.

However, the prognosis for patients with malignant acanthosis nigricans is often poor. These tests may include blood glucose tests or fasting insulin tests. In rare cases, your doctor may perform other tests, such as a small skin biopsy , to rule out other possible causes.

Your doctor may also prescribe medications to help bring your blood glucose under control. If the condition is caused by medications or supplements, your doctor may have you discontinue them or suggest substitutes. The discolored skin patches will usually fade when you find the cause and get it under control.

The right diet for prediabetes ». If you are concerned with the appearance of your affected skin, there are cosmetic treatments available. Treatments include:. These treatments can improve the appearance of acanthosis nigricans but will not cure the condition. Maintaining a healthy lifestyle can usually prevent acanthosis nigricans. Losing weight , controlling your diet, and adjusting any medications that are contributing to the condition are all crucial steps.

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